AIM: Lab- How can a mutation in the DNA sequence affect a sequence of amino acids? How does this affect the final protein product?
Today we did an in-class lab. Most people did not finish the analysis, and it was assigned for HOMEWORK. The lab is attached below. You will have until this Friday to complete the lab. I know that some people need assistance with the questions. Please stop by during office hours for tutoring.
Key Concepts:
- There are 3 types of mutations that may occur in a sequence of DNA bases.
Insertion- a base, or sequence of bases is added to the DNA (strand will be longer)
Deletion- a base, or sequence of bases is removed from the DNA (strand will be shorter)
Substitution- a base, or sequence of bases is replaced by different bases (strand will be the same length)
- A gene is a segment of DNA that codes for a protein
- Genes code for mRNA, which codes for an amino acid sequence
- Amino acids are the building blocks of proteins
- The sequence of amino acids will determine the specific shape a protein has
- If a DNA sequence is mutated, the amino acid sequence may or may not be affected depending on the mutation.
- Enzymes are proteins!
- If any loses its specific shape, it will no longer be able to perform their job
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