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Williamsburg High School for Architecture and Design

Redefining Career & Technical Education in New York City Since 2009

You are here: Home / Teacher Posts / 3/11

3/11

March 11, 2014 By Ms. Bruno

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AIM: Lab- How can a mutation in the DNA sequence affect a sequence of amino acids? How does this affect the final protein product?

Today we did an in-class lab. Most people did not finish the analysis, and it was assigned for HOMEWORK. The lab is attached below. You will have until this Friday to complete the lab. I know that some people need assistance with the questions. Please stop by during office hours for tutoring.

Key Concepts:

  • There are 3 types of mutations that may occur in a sequence of DNA bases.

Insertion- a base, or sequence of bases is added to the DNA (strand will be longer)

Deletion- a base, or sequence of bases is removed from the DNA (strand will be shorter)

Substitution- a base, or sequence of bases is replaced by different bases (strand will be the same length)

  • A gene is a segment of DNA that codes for a protein
  • Genes code for mRNA, which codes for an amino acid sequence
  • Amino acids are the building blocks of proteins
  • The sequence of amino acids will determine the specific shape a protein has
  • If a DNA sequence is mutated, the amino acid sequence may or may not be affected depending on the mutation.
  • Enzymes are proteins!
  • If any loses its specific shape, it will no longer be able to perform their job

[gview file=”https://www.whsad.org/wp-content/uploads/2014/03/7-mutation-lab.docx”]

 

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About Ms. Bruno

Ms. Bruno has been an Assistant Principal at Williamsburg High School for Architecture and Design since 2009. She oversees the departments of Science, Mathematics, Architecture and Design (Career and Technical Education (CTE)), Physical Education and Health. She can be reached at 718-388-1260 ext. 2080, or bruno@whsad.org.

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